Cutaneous manifestations in Moyamoya angiopathy: A review

Background and purpose: Moyamoya angiopathy (MA) is a progressive cerebrovascular disease with poorly understood pathophysiology. It mainly characterized by bilateral stenosis of the terminal intracranial part supraclinoid internal carotid arteries proximal parts middle anterior cerebral arteries. This results in early-onset ischemic or hemorrhagic strokes. The may be idiopathic (known as disease) associated other heritable acquired conditions, including type 1 neurofibromatosis RASopathies, sickle cell disease, Down syndrome, autoimmune disorders syndrome). Apart from brain, organ manifestations cutaneous ones have also been described MA patients. Materials methods: A literature research on PubMed was performed for articles mentioning association published between 1994 October 2020. Conclusion: present review summarizes associations well coincidental dermatological findings seen Those include changes epidermis, dermis, skin appendages example café-au-lait spots, hypomelanosis Ito, livedo racemosa, hemangiomas, premature graying hair, chilblains etc.